01 Apr

SuFEx Handle Fragment Library

melius Company

We’re pleased to share the SuFEx Handle Fragment Library, developed in collaboration between Melius Organics and OTAVA ltd.

This library comprises 74,543 fluorosulfate and sulfamoyl fluoride-containing fragments, designed to enable covalent modification of proteins via Sulfur(VI) Fluoride Exchange (SuFEx) chemistry. As a second-generation “click” reaction, SuFEx provides robust, selective reactivity under mild conditions, making it particularly suitable for fragment-based covalent ligand discovery.


🔹 Targets key nucleophilic residues such as lysine, tyrosine, and histidine
🔹 Facilitates covalent inhibitor development, enzyme profiling, and bioconjugation
🔹 Well-suited for applications in chemical biology, proteomics, and structure-based drug design
🔹 All fragments are feasible, synthetically accessible, and available for virtual or physical screening
🔹 Compounds are prepared on demand using in-stock building blocks with a typical turnaround of ~3 weeks


The structural diversity and electrophilic tuning of this library make it a valuable resource for exploring underexploited covalent binding strategies, especially beyond cysteine targeting.

Read more: https://meliusorganics.com/sufex-fragment-library/
PDF brochure: https://meliusorganics.com/wp-content/uploads/2025/03/sufex-fragment-library.pdf

18 Dec

Melius Organics has been included in APTE Top 100 Startups 2024

melius Company

🎉 What a great way to close the year! 🎆

Melius Organics has been included in the APTE Top 100 Startups list for 2024, launched by The Association of Science and Technology Parks of Spain (APTE) 🚀

This recognition highlights the top 100 startups located in scientific and technological parks across Spain, showcasing innovation in cutting-edge sectors such as biotechnology, artificial intelligence, clean energy, health, space, agrotech, blockchain, sustainability, and more.

We are proud to be part of an inspiring group of innovators and entrepreneurs! 💡

🌟 Special thanks to APTE and REDESSA, which help bring entrepreneurial ideas to life.

You can explore the full list of recognized startups here 👉https://lnkd.in/dBSz9-Za

 

20 Aug

Melius Organics is Now Officially Founded

melius Company

We are very happy to inform you that today Melius Organics has finally transitioned into a fully established company!

Our Journey So Far
Melius Organics began as a start-up project with the vision to foster the discovery of new molecules. From the beginning, our goal has been to provide high-quality reagents and offer bespoke services. Strategically located at Camp de Tarragona, Spain, we have had the opportunity to work with some of the best experts and institutions in the field.

What This Means for Us—and for You
The official founding of Melius Organics marks a significant milestone in our journey. It enables us to expand our operations, enhance our collaborations, and better serve our clients. Now, as a legally established company, we are ready to bring our solutions to the market.

Looking into the Future
We are very excited about what the future will bring now that we have taken this big step. We look forward to continuing with our work in creating new molecules, refining our processes, and contributing to progress of organic chemistry.

Thank you to everyone who has supported us on this journey—from our early days to this moment as a fully established company. We couldn’t have done it without you, and we’re excited to continue growing together.

Stay tuned for more news!

Jordi, Miguel & Omar

09 May

Melius Organics has been selected for REDESSA incubator 4th Edition

melius Company

We are thrilled to announce that our project has been selected to participate in the 4th edition of REDESSA’s TIC and Foodtech Incubator! Out of the twenty projects that applied, we are one of the ten innovative start-ups chosen to join this program.

REDESSA’s TIC and Foodtech Incubator is dedicated to propelling technology-based projects that have the potential to make a significant impact on the region. The incubator provides an invaluable platform for start-ups, offering a range of activities and support to help us succeed. This includes a hybrid incubation process featuring a bootcamp, personalized mentoring, seminars on leadership skills, effective presentations and storytelling, expert talks on marketing, legal aspects, fundraising, public investment, and networking events. Additionally, there are new financing options and enhanced support for online sales and sales planning.

We are excited about the opportunities this incubator presents and are committed to leveraging this experience to bring our innovative solutions to market. Stay tuned for updates on our journey and progress as part of REDESSA’s TIC and Foodtech Incubator.