SuFEx Handle Fragment Library
We’re pleased to share the SuFEx Handle Fragment Library, developed in collaboration between Melius Organics and OTAVA ltd. This library comprises 74,543 fluorosulfate and sulfamoyl fluoride-containing fragments, designed to enable covalent modification of proteins via Sulfur(VI) Fluoride Exchange (SuFEx) chemistry. As a second-generation “click” reaction, SuFEx provides robust, selective reactivity under mild conditions, making it […]