Fluorinated compounds

We have expertise synthesizing molecules with relevant biological roles.

We gather decades of experience in fluorine chemistry.

We can access unique chemical spaces including emerging motifs used in drug development, agrochemicals and material sciences.

Our products offer new properties and opportunities for IP protection.

From
problem

Common challenges

New and more selective covalent inhibitors are needed for drug discovery campaigns
In lead optimization, metabolic stability and bioavailability improvement are challenging
Modern drug development needs to cover new chemical spaces

To solution

Fluorinated motifs help reaching new chemical spaces with improved pharmacokinetic properties. At Melius Organics we are skilled in preparing complex fluorinated molecules, building blocks, and covalent click inhibitors (SuFEx).

Selected examples

Reagents and building blocks

Emerging fluorinated motifs

Late stage functionalization

Covalent warheads (SuFEx)

Virtual screening of >70.000 compounds

Click chemistry
handles

SF₅ compounds

Small building blocks

PFAS replacement

What our clients say:

“Melius Organics delivered all compounds on schedule with complete data, and their chemistry expertise was invaluable throughout. I would definitely recommend their services.”