Analytical standards

Whether they are commercially available or not, we can prepare high-quality analytical standards.

From
problem

Common challenges

The reference standard you need is not commercially
available, or the price is prohibitive.
Your method validation requires isotopically labelled
internal standards for LC-MS/MS, PK/DMPK,
or metabolomics work.
You have identified an impurity, degradant, or unknown
metabolite and need the authentic standard to confirm
structure and quantify it.

To solution

We design and synthesise analytical standards tailored
to your method.

You discuss your project directly with the chemists
doing the synthesis, so the specifications, the labelling
pattern, and the delivery format match what your
instrument and workflow actually need.

Metabolites

Custom synthesis of metabolites and biotransformation products for biological and clinical research. We deliver full analytical characterization to support metabolomics studies and bioanalytical validation.

Stable isotopes
(²H, ¹³C, ¹⁵N, ³⁴S)

Deuterium, ¹³C, ¹⁵N, and ³⁴S labeled compounds for pharmacokinetic studies and mass spectroscopy internal standards. High isotopic purity and structural integrity ensure reliable results for drug and metabolic pathway research.

Imaging probes (¹⁹F)

Synthesis of ¹⁹F-labeled molecular probes for non-radioactive imaging applications. Our fluorine incorporation expertise supports the development of MRI contrast agents and fluorinated biomarkers or medical research and diagnostic applications.

Impurities

What our clients say:

“The work and our relationship with Melius Organics have been excellent. From the very beginning, communication has been constant and they responded very promptly to our need for a non-commercial chemical compound with the required purity for quantitative analysis. They are highly recommendable.”