Pentafluorosulfanyl (SF5) technology
The pentafluorosulfanyl group: the new CF3 group
The pentafluorosulfanyl (SF5) group is considered an emerging motif in medicinal chemistry and materials science. Often referred to as the “super CF3” due to its highly fluorinated, lipophilic nature, SF5 offers unique properties that set it apart from other groups, with high potential in research and development of new drugs.
Additionally, it is not classified as a PFAS, making it more sustainable.
The SF5 group in drug candidates
Selected products
We are currently expanding our catalog of SF5 products, with a primary focus on sp³-rich fragments to cover a broader area of chemical space.
Additionally, we are working on related technologies, such as the underexplored -OSF5
fragment, to introduce new and innovative motifs into your research.
Our expertise
We have experience in preparing and working with SF5 compounds, offering high-quality products
and innovative solutions tailored to your research needs. Whether you’re exploring new applications
in medicinal chemistry or material science, our team is equipped to support your projects with expert
guidance and custom synthesis services.
Gaseous regents
Flow chemistry
Photochemistry
Custom synthesis
SF5-sp3 blocks
