Melius Organics

Fluorinated compounds

We have expertise synthesizing molecules with relevant biological roles.

We gather decades of experience in fluorine chemistry.

We can access unique chemical spaces including emerging motifs used in drug development, agrochemicals and material sciences.

Our products offer new properties and opportunities for IP protection.

From
problem

Common challenges

  • New and more selective covalent inhibitors are needed for drug discovery campaigns
  • In lead optimization metabolic stability and bioavailability improvement are challenging
  • Modern drug development needs to cover new chemical spaces

To solution

Fluorinated motifs help reaching new chemical spaces with improved pharmacokinetic properties. At Melius Organics we are skilled in preparing complex fluorinated molecules, building blocks, and covalent click inhibitors (SuFEx).

Selected examples

Reagents and building blocks
Emerging fluorinated motifs
Late stage functionalization
Covalent warheads (SuFEx)
Virtual screening of >70.000 compounds
Click chimestry handles
SF5 compounds
Small building blocks
PFAS replacement

Radical reagent

CF2

SRF reagent

blocks

What our clients say:

“Melius Organics delivered all compounds on schedule with complete data, and their chemistry expertise was invaluable throughout. I would definitely recommend their services.”
Dr. Josep Roma – P. I. Translational Research in Child and Adolescent Cancer Research Group

From idea to grams

free & confidential